zapA [2017-8-11 16:0:3]

positive modulator of FtsZ Z ring assembly and stability

Locus: BSU28610

Isoelectric point: 7.17

Molecular weight: 9.73 kDa

Protein length: 85 aa

Gene length: 255 bp

Function: control of Z-ring formation

Product: Z-ring-associated protein

Essential: no

Synonyms: yshA

Genomic Context

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Categories containing this gene/protein

• Cellular processes → Cell envelope and cell division → Cell division → Other genes

Gene

Coordinates: 2,925,640 → 2,925,897

Phenotypes of a mutant

• a zapA ezrA double mutant forms filamentous cells PubMed
• a whiA zapA double mutant grows poorly, and the cells are filamentous (due to a defect in Z ring assembly) PubMed
• the defects of the whiA zapA double mutant can be suppressed by inactivation of either gtaB, pgcA, or ugtP PubMed

The protein

Protein family

• Type 2 subfamily (according to Swiss-Prot)

Structure

• 1W2E (from Pseudomonas aeruginosa) PubMed

Localization

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operons

• Genes: zapA-yshB-polX-mutSB-yshE
  Description: PubMed

  Regulation

  • constitutively expressed PubMed

Biological materials

Mutant

• MGNA-B027 (yshA::erm), available at the NBRP B. subtilis, Japan

References

Reviews

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Original Publications

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